Archive for January, 2010

50% of UK Vitamin D deficient

Friday, January 29th, 2010 | Tags: , , , , , , , , , , , , , , , ,
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Spending too long indoors, applying excessive sun screen and the changing ethnic population is causing precariously low levels of Vitamin D in parts of the UK, warn Professor Simon Pearce and Dr Tim Cheetham at Newcastle University.

“More than 50% of the adult population have insufficient levels of vitamin D and 16% have severe deficiency during winter and spring,” they say. “The highest rates are in Scotland, Northern Ireland and northern England. People with pigmented skin are at high risk as are the elderly, obese individuals and those with malabsorption.”

The research published in the British Medical Journal, has found that the most commonly affected are people of Asian and African descent who live in the North; a key part of the research focused on young Somalis who live in east Newcastle.

Other causes include consistent sun screen application instead of allowing 20 to 30 minutes exposure to the sun two or three times a weeks, staying indoors all the working day and children sitting in front of computer games rather than playing outdoors.

Pearce has written to the Department of Health proposing Vitamin D is added to milk. It is already added to artificial baby milk.

Rickets are associated with the 19th century and young workers in industrial cities. The disease causes softening of the bones and muscle weakness. When a child has rickets, there is not enough mineral in the bones, making them soft and weaker.

Some vitamin D is obtained from certain foods: egg yolk, liver, oily fish such as sardines, herring, tuna, salmon and mackerel. A diet low in these foods will contribute to a lack of vitamin D but the main cause of the problem is lack of sunlight on the skin.

Italian group offers $4.5M to fund new MS research on CCSVI

Friday, January 29th, 2010 | Tags: , , ,
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The Italian Multiple Sclerosis Foundation today announced it will allocate up to $4.5 million to fund ongoing research into CCSVI, a condition linked to Multiple Sclerosis.

The foundation says it is accepting research proposals until March 8 from scientists interested in studying “chronic cerebro-spinal venous insufficiency,” a newly-discovered condition uncovered by a team at the University of Ferrara in Italy and lead scientist Dr. Paolo Zamboni.

“We await proposals from groups of Italian researchers, in particular by the research groups that are already active with Prof. Zamboni,” the foundation said in an Italian news release.

Zamboni’s team believes that CCSVI causes veins in the neck and upper chest to twist, narrow or become blocked; in some cases, these veins never form at all. The result is poor blood drainage from the brain. Zamboni has found that more than 90 per cent of patients with MS have these malformed veins, and improper blood flow from the brain.

Roberta Amaedo, president of the Italian Association for Multiple Sclerosis, said in the release: “We need certainty about the relationship between MS and CCSVI and on the clinical course that this can cause, and on that, clinical trials will make an important contribution.”

The association also cautioned patients against seeking endovascular or surgical procedures to open these blocked veins outside of controlled research studies.

Higher vitamin D levels may be linked to lower risk of bowel cancer

Monday, January 25th, 2010 | Tags: , , , , , , , , , , , ,
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25/01/2010

People with higher levels of vitamin D appear to be significantly less likely to develop bowel cancer, a new European study has found.

Researchers from a number of institutes in Europe, including Imperial College London, analysed data contained in the European Prospective Investigation into Cancer (EPIC) study, which involved over 520,000 people in ten countries.

Participants provided blood samples and information on their diet and lifestyle between 1992 and 1998, before being followed for several years.

At the time of the analysis, information from 1,248 people who had been diagnosed with bowel cancer was compared with information on 1,248 healthy controls also involved in the study.

The researchers discovered that people with the highest concentrations of vitamin D in their blood had a 40 per cent reduced risk of bowel cancer compared with those recording the lowest levels of the vitamin.

Writing in the British Medical Journal, the researchers concluded that vitamin D may be associated with a protective effect against bowel cancer.

However, they noted that insufficient research has been carried out into the long-term health impact of having high levels of vitamin D in the blood and that further research is needed both to confirm any beneficial effect on bowel cancer risk and to rule out any potential adverse effects.

Ed Yong, head of health evidence and information at Cancer Research UK, said: “This large study confirms that low levels of vitamin D are linked to an increased risk of bowel cancer. More research is needed to clarify whether vitamin D alone directly prevents this disease or if having higher levels of vitamin D means people are generally healthier.

“Either way, we know that vitamin D is important for good health,” he continued.

“Enjoying the sun safely while taking care not to burn should help people strike a balance between making enough vitamin D and avoiding a higher risk of skin cancer. People can also top up their vitamin D levels by eating foods like oily fish (such as salmon, trout or mackerel), or by taking supplements after talking to their GP.”

Reference

  • Jenab, M. et al (2010). Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study BMJ, 340 (jan21 3) DOI: 10.1136/bmj.b5500

Vitamin D link to bowel cancer risk

Monday, January 25th, 2010 | Posted in Uncategorized

People who have more vitamin D in their blood are less likely to develop bowel cancer than those with low levels, researchers have said.Skip related content

According to a study published in the British Medical Journal, those with the highest levels of the vitamin were at 40% lower risk of developing the disease compared with those with the lowest levels.

It comes after medical experts expressed concern on Thursday about the rising number of cases of rickets – caused by vitamin D deficiency – and called for it to be added to milk and other food products.

The main source of vitamin D is sunlight, through skin exposure, but it is also present in a small number of foods, such as oily fish or cod liver oil.

The research team said that although the latest study provides evidence of a link between vitamin D and bowel cancer, it does not prove that taking vitamin D supplements prevents the disease.

More studies are needed to find out the potential impact on other cancers and the effects of taking extra vitamin D doses, scientists said.

Dr Panagiota Mitrou, science programme manager for the World Cancer Research Fund, said: “This is the biggest ever study on this subject and there is now quite a lot of evidence from studying populations that people who have low levels of vitamin D are more likely to develop bowel cancer.

“The next step is to carry out new clinical trials to try to confirm whether vitamin D supplementation can reduce the risk of bowel cancer and whether there are any harmful effects of higher levels of vitamin D.

“But we need to emphasise that, for the moment, the findings need to be treated with caution and they are certainly not enough evidence to suggest that we should be taking supplements to increase levels of vitamin D.

“The best advice for reducing risk of bowel cancer remains to stop smoking, maintain a healthy weight, be regularly physically active, to eat more fibre and less red and processed meats and to cut down on alcohol.”

Newcastle University experts want Vitamin D put in food

Monday, January 25th, 2010 | Posted in Uncategorized

Vitamin D should be added to milk and other food products to halt a rise in cases of rickets in children, say experts at Newcastle University.

The vitamin, produced when skin is exposed to sunlight, is also found in a small number of foods, and deficiency can cause bone deformation.

One reason for an increase in cases is thought to be the popularity of indoor activities, such as computer gaming.

Professor Simon Pearce said a change in public health policy was needed.

A lack of the vitamin within the traditional UK diet is also thought to be a factor – it can be found in oily fish such as salmon, mackerel, sardines and herring.

Writing in the British Medical Journal, Professor Pearce and colleague Dr Tim Cheetham said Vitamin D deficiency had become “disturbingly common” in the UK in recent years.

‘Entirely preventable’

Dr Cheetham said: “I am dismayed by the increasing numbers of children we are treating with this entirely preventable condition.

“Fifty years ago, many children would have been given regular doses of cod liver oil, but this practice has all but died out.”

Half of all adults in the UK have a deficiency in the winter and spring, with one in six having severe deficiency.

The problem is worse in northern regions and could be part of the reason for the health gap between the north and south, according to the university figures.

Professor Pearce said health professionals have been slow to deal with the problem.

He added: “We believe that a more robust approach to statutory food supplementation with vitamin D, for example in milk, is needed in the UK, as this measure has already been introduced successfully in many other countries in similar parts of the world.”

A Department of Health spokesman said: “Vitamin D supplements are recommended for some people at risk of vitamin D deficiency and people at risk of not getting enough exposure to sunlight.

“The Scientific Advisory Committee on Nutrition has advised that research into the link with chronic disease is inconclusive and further work is needed before any definitive conclusions can be drawn.”

http://news.bbc.co.uk/1/hi/england/tyne/8472469.stm

Experts call for Vitamin D in milk

Sunday, January 24th, 2010 | Tags: , , , , , , , , , , , , , ,
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Low Vitamin D levels are associated with greater risk of MS relapse

Thursday, January 21st, 2010 | Tags: , , , , , , , , , , ,
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Low vitamin D blood levels are associated with a significantly higher risk of relapse attacks in patients with multiple sclerosis (MS) who develop the disease during childhood, according to a study conducted by researchers from the University of California, San Francisco.

“We have known for some time that vitamin D insufficiency is a risk factor for developing MS, but this is the first study to assess whether vitamin D levels influence the disease course of those who already have MS,” said lead author Ellen Mowry, MD, MCR, a clinical instructor of neurology at the UCSF Multiple Sclerosis Center.

The study, which is now published online by the “Annals of Neurology” and is available at http://www3.interscience.wiley.com/journal/123246501/abstract , demonstrates that an increase in vitamin D levels by 10 nanograms per milliliter of blood (ng/mL) corresponds with a 34 percent decrease in the rate of subsequent relapses.

In other words, raising the vitamin D level of a person with MS by 15 ng/mL, which requires about 2,000 international units of vitamin D supplementation a day, could theoretically cut a patient’s relapse rate in half, explained Mowry.

“Although we do not yet know if vitamin D supplementation will be beneficial for MS patients, the fact that there is a clear association between vitamin D levels and relapse rate provides strong rationale for conducting a clinical trial to measure the potential impact of supplementation,” she said.

“This is an exciting finding because it indicates that it is very possible for vitamin D supplementation to have a profound impact on the course of this disease,” said senior author Emmanuelle Waubant, MD, PhD, an associate professor of neurology at UCSF and director of the Regional Pediatric MS Center at UCSF Children’s Hospital. Waubant said she expects similar findings in adult patients with MS.

Multiple sclerosis is a chronic and often disabling disease that affects the central nervous system, which comprises the brain, spinal cord and optic nerves. A type of autoimmune disorder, MS causes the body’s own defense system to break down a substance called myelin, which surrounds and protects nerve fibers.

Although MS occurs most commonly in adults, a small proportion of cases are diagnosed in children and adolescents. According to the National MS Society, two to five percent of all people with MS experience their first symptoms before the age of 18.

The researchers measured vitamin D levels through blood samples from 110 patients whose MS symptoms began at age 18 or younger. The patients were seen at either UCSF Children’s Hospital or the State University of New York Stony Brook’s Regional Pediatric MS Center of Excellence – two of six multidisciplinary referral centers in the United States sponsored by the National MS Society.

After providing the initial blood sample, patients were followed for an average of 1.7 years, during which the researchers recorded the total number of relapses each patient experienced. According to Mowry, a relapse or flare-up of MS causes new neurologic symptoms or the worsening of old ones, such as impaired vision, problems with balance, or numbness. Relapses can be very mild or severe enough to interfere with a person’s ability to function.

During the follow-up period, the researchers assessed the patients’ relapse rates and vitamin D levels after controlling for such factors as age, gender, race, ethnicity, use of MS treatments and the duration of follow-up care.

“If we are able to confirm that vitamin D supplementation is an effective treatment, my hope is that it will help improve the quality of life for all MS patients,” Mowry said.

In addition to a randomized clinical trial of vitamin D supplementation in MS patients, Mowry said further studies are also needed to determine the mechanism by which vitamin D affects inflammatory processes and, in turn, eases symptoms of MS.

Additional co-authors from UCSF include Dorothee Chabas, MD, PhD; Jonathan Strober, MD; Jamie McDonald, BS; Jorge Oksenberg, PhD, and Peter Bacchetti, PhD. Co-authors from other institutions are Lauren Krupp, MD; Maria Milazzo, MS, CPNP, and Anita Belman, MD, all of the Pediatric MS Center, State University of New York at Stony Brook.

The study was supported by a National MS Society Sylvia Lawry Fellowship Award and an additional grant from the National MS Society.

Source: PRWEB (21/01/10)

Baby steps towards better regulation!

Friday, January 15th, 2010 | Posted in Uncategorized

A rebuff for Heinz over an outrageous baby formula TV ad is bad news for food corps and their ever-more-sophisticated tweaks of parental guilt. But Heinz needs a proper spanking

Heinz has received an embarrassing ticking-off from the Advertising Standards Authority for the nauseating TV advert for its baby milk, Nurture, above. The ASA said on Monday that the claim that the formula would support growth in the brain, body and immune system of a baby was “unsubstantiated” and “unacceptable”.

Campaigners for honest food are delighted. This is a boost in the next front in the long-running war over children’s food claims: promises that food supplements can aid mental development. (How long-running? In the 1890s John Harvey Kellogg said that his cornflakes would prevent masturbation in young men, while in 1903 Grape Nuts promised a cure for malaria and loose teeth.)

Already Nestle’s Gerber brand in the United States is marketing follow-on purees for toddlers with the words “helps support brain and eye development” prominent on the packet. This claim – accepted by the authorities in the US – is based on research around DHA and other forms of Omega-3 oils.

Gerber baby foodGerber baby food which, the manufacturers claim, helps support brain and eye development. Photograph: Alex Renton

Despite scepticism over on this side of the Atlantic – one eminent scientist told me recently the claim that DHA could help nerve system development and cognitive function was “bullshit” – manufacturers have been preparing for what they believe will be a positive ruling from theEuropean foods standards body soon. Will the ASA ruling upset that process?

For now, it is three cheers for the ASA, which has been showing its teeth on food manufacturers’ porkies lately. Christine Haigh of the Children’s Food Campaign points out the resemblance with the case last October in which Danone’s adverts claimed that Actimel was “scientifically proven to help support your kids defences” were ruled against. “We believe the Food Standards Agency needs to investigate how widespread this practice is,” says Haigh.

Sadly the ASA, like the Press Complaints Commission, is more bark than bite. It cannot make Heinz and its ad agency Abbott Mead Vickers BBDO say sorry to those poor parents it bullied to buy Nurture, which costs 70% more than the Farley’s product it replaced when launched in July 2008. In fact, a proper self-regulatory body would make “agency of the year 2009″ AMV BBDO pay back their fee to the mums and dads. Shouldn’t it?

Study shows beneficial effects of fortified milk on child’s cognitive development

Friday, January 15th, 2010 | Tags: , , , ,
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Singapore, January 14, 2010: According to a study, fortification of milk given to children of preschool age showed significant improvement in cognitive and executive function at school age (6-8 years). This study, sponsored by Fonterra, the world’s largest dairy exporter from New Zealand, is a continuation of an initial study that was carried out to evaluate the effects of the same micronutrient fortified milk on morbidity in young, preschool children.

An intervention study was carried out to evaluate the effects of micronutrient fortified milk on cognitive function in young children. The participants included 375 children aged 6-8 years, randomly allocated to receive the fortified milk or control milk. The fortified milk included a specific combination of zinc, iron, selenium, copper and vitamins A, C and E.  Through the usage of the Wisconsin Card Sorting Test (WCST), children in the fortified milk group were found to have better cognitive and executive function. The fortified milk children exhibited: 14% lower odds of making errors,

The study examined the long term effects of early micronutrient supplementation for one year during the early preschool years on subsequent executive functioning of the children at ages of 6 to 8 years of age. Results showed that consumption of milk fortified with specific micronutrients was associated with improvement in sub-measures of executive functioning using WCST, as compared to the control group of children. These findings are consistent with previously reported observational studies of long-lasting benefits of early nutritional supplementation on cognition especially higher mental functions when the children reached school age.

Compared to the control group children, children who received the specific micronutrient intervention had 14 % lower odds (95% CI: 10-17%) of making errors, 8% lower perseverative errors (95% CI: 5-11%), and 10% lower non-perseverative errors (95% CI: 6-14%). The conceptual level responses were 26% higher (95% CI: 21-31%) in the micronutrient intervention group than the control group.

This study demonstrates beyond reducing the impact of acute childhood illness and improving nutritional status, consumption of specific fortified milk in early childhood showed improved cognitive ability later in life.

Prof Sunil Sazawal, a leading expert in child nutrition and health and has served as a World Health Organisation (WHO) consultant numerous times said, “Because nutrition plays such a vital role in the process of cognitive development, micronutrient deficiencies can have a serious impact. For example, deficiencies of iron and zinc, prevalent even among well-nourished children in Asian regions, are postulated to have a negative effect on the developmental potential of these children.”

Heinz ad banned !

Friday, January 15th, 2010 | Posted in Uncategorized

A TV ad campaign for Heinz baby products that made misleading claims about their health benefits has been banned by the advertising watchdog.

The TV ad, by the agency Abbott Mead Vickers BBDO, promoted Heinz Nurture infant formula and milk by stating that a baby needed a “special combination of nutrients to sustain the incredible growth in its brain, body and immune system”. It claimed that Heinz had developed Nurture to “provide for those three essential aspects of growth” and that it helped “nourish, protect and develop your baby”

The Advertising Standards Authority received three complaints that the ad made claims about immunity and development in children that the product could not justify.

Heinz said that the “nurture” claim was based on the formulation’s milk protein for growth and calcium for healthy teeth and bones; the “protect” claim came from elements including iron, prebiotics and nucleotides that protect the immune system; and “develop” came from the inclusion of omega-3 and omega-6, which helped brain and eye development.

The ASA said that Heinz’s ad strategy implied a specific health benefit from the use of Nuture. The watchdog pointed out that the ad was broadcast in July 2008 – after new European regulations came into force relating to nutrition and health claims for foods, and said it was “concerned that the evidence submitted was not sufficiently robust to support the product’s claims in relation to children’s immunity and development. We concluded, therefore, that the claim was unsubstantiated and the ad was unacceptable.”