Posts Tagged ‘autism’

Pregnant mothers should be given vitamin D to help safeguard babies’ health

Saturday, July 3rd, 2010 | Tags: , , , , , , , , , , , , , , , , , , ,
Posted in Uncategorized

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Researchers at the UCL Institute of Child Health (ICH) are calling for the swift reintroduction of vitamin D supplements to pregnant women in the UK.

In an article published online today by the British Journal of Nutrition (BJN), the authors argue that despite a growing body of evidence that links vitamin D deficiency to complications in pregnancy and poor neonatal health, the UK remains the only one of 31 European countries that doesn’t have a set vitamin D recommendation for women of reproductive age, whilst also failing to endorse a daily supplement to expectant mothers.
Dr Elina Hyppönen, reader in epidemiology and public health at the ICH and a co-author explains, “The incidence of vitamin D deficiency in pregnant women in Britain is unacceptably high, especially during winter and spring.  This is compounded by a lack of exposure to sunlight and the limitations of an average diet to meet the optimal need.

“In the most severe cases, maternal vitamin D deficiency can be life threatening to a newborn. We believe that the routine provision of a daily supplement throughout pregnancy would significantly decrease the number of mothers who are clearly vitamin D deficient, reducing related serious risks to their babies.

“Our take on vitamin D supplementation in the UK has seen many changes over the decades and we can see clearly from past experience that a proactive approach to supplementation has coincided with a much lower incidence of deficiency linked diseases such as infantile hypocalcaemia and rickets.”
Current data for the UK shows that women are more likely to be vitamin D deficient than men (9.2 and 6.6 per cent respectively). Pregnancy poses a particularly high risk situation, with one in four pregnant mothers being vitamin D deficient ( below 25nmol/l) during winter and spring, with nearly all (90 per cent) having concentrations considered insufficient (below 50nmol/l).
In the article, Dr Hyppönen and her co-author, Barbara J Boucher (Queen Mary, University of London) draw on historical data that supports the case for a daily dose of at least 10µg of vitamin D to prevent vitamin D deficiency in pregnant mothers, and recent evidence suggesting potentially wide-ranging benefits for the prevention of deficiency for the health of the mother and her child.
“This risk of vitamin D deficiency is largely being overlooked by our health professionals. Under a current government scheme, pregnant women who are on a low income are entitled to receive supplements free of charge, but there is no strong evidence to suggest that this group are at greater risk.
“What’s needed is a unified approach that will ensure that all expectant mothers, regardless of their economic status, are informed of the benefits of taking a regular supplement throughout pregnancy.”

Avoidance of vitamin D deficiency in pregnancy in the United Kingdom: the case for a unified approach in National policy, Elina Hyppönen1 and Barbara J. Boucher2: http://journals.cambridge.org/bjn/vitD

Researchers endorse, modify vitamin D theory of autism

Tuesday, June 29th, 2010 | Tags: , , , , ,
Posted in External News Articles

24 June 2010

A Scientific American article asks, “What if Vitamin D Deficiency is a Cause of Autism?” How could vitamin D deficiency during pregnancy cause autism, a genetic disease? Indeed, five researchers at Harvard, led by Dr. Dennis Kinney, recently endorsed and then modified the vitamin D theory of autism.

Very recently, Dr. Darryl Eyles, of the University of Queensland, added his name to growing list of scientists who agree that vitamin D deficiency plays an important role in autism. Writing in Acta Paediatrica, arguably the most read pediatric journal in the world, Dr. Eyles praised the vitamin D theory of autism as being “parsimonious,” with the animal studies he has conducted over the last decade.

For the last 15 years, geneticists have tried and failed to find a common structural genetic abnormality in autism. What they have found is evidence of genetic damage; the genetic code is not properly regulated in autism, with multiple genes not being expressed, probably due to an environmental injury. As Dr. Kinney reports, vitamin D’s mechanism of action is protection of the genome with direct regulation more than 1,000 human genes.

If the gestational and early childhood vitamin D deficiency theory of autism is true, the tragedy is more poignant in that physicians could prevent the disease with adequate daily doses of vitamin D during pregnancy and early childhood. Just as important, vitamin D’s mechanism of action implies a treatment effect in autistic children.

This month, Acta Paediatrica, published yet another article on vitamin D and autism. This paper is open access; the pdf is free to download. In the paper, Dr. Cannell reviews the evidence of vitamin D’s involvement in autism, including evidence published after his original 2007 paper.

SOURCE Vitamin D Council

Scientific American explores Role of Vitamin D in Autism

Sunday, June 27th, 2010 | Tags: , , , , ,
Posted in Uncategorized

Scientific American Article Explores the Role of Vitamin D in Autism

A Scientific American article asks, “What if Vitamin D Deficiency is a Cause of Autism?” (1) How could vitamin D deficiency during pregnancy cause autism, a genetic disease? Indeed, five researchers at Harvard, led by Dr. Dennis Kinney, recently endorsed and modified the vitamin D theory of autism. (2)

Dr. Darryl Eyles, of the University of Queensland, added his name to growing list of scientists who agree that vitamin D deficiency plays an important role in autism. (3) Writing in Acta Paediatrica, arguably the most read pediatric journal in the world, Dr. Eyles praised the vitamin D theory of autism as being “parsimonious,” with the animal studies he has conducted over the last decade.

For the last 15 years, geneticists have tried and failed to find a common structural genetic abnormality in autism. What they have found is evidence of genetic damage; the genetic code is not properly regulated in autism, with multiple genes not being expressed, probably due to an environmental injury. As Dr. Kinney reports, vitamin D’s mechanism of action is protection of the genome with direct regulation more than 1,000 human genes.

If the gestational and early childhood vitamin D deficiency theory of autism is true, the tragedy is more poignant in that physicians could prevent the disease with adequate daily doses of vitamin D during pregnancy and early childhood. Just as important, vitamin D’s mechanism of action implies a treatment effect in autistic children.

This month, Acta Paediatrica, published yet another article on vitamin D and autism. This paper is open access; the pdf is free to download. (4) In the paper, Dr. Cannell reviews the evidence of vitamin D’s involvement in autism, including evidence published after his original 2007 paper. (5)

  1. Glaser G. What If Vitamin D Deficiency Is a Cause of Autism? Sci Amer April 24, 2009.
  2. Kinney DK, Barch DH, Chayka B, Napoleon S, Munir KM. Environmental risk factors for autism: do they help cause de novo genetic mutations that contribute to the disorder? Med Hypotheses 2010;74:102-6.
  3. Eyles DW. Vitamin D and Autism, Does skin colour modify risk? Acta Paediatr 2010 Mar 8.
  4. Cannell JJ. On the Aetiology of Autism. Acta Paediatrica. ISSN 0803–5253, May 2010.
  5. Cannell JJ. Autism and Vitamin D. Med Hypotheses 2008;70(4):750-9. Epub 2007 Oct 24.

Source: Vitamin D Council